Synativ Clinical Innovation Center
Synativ is an independent clinical initiative dedicated to developing structured, non-invasive therapeutic approaches focused on nervous system regulation, chronic pain, and functional recovery.
Based in Jerusalem, Synativ works with patients presenting complex conditions such as fibromyalgia, migraine, chronic pain, and stress-related dysfunctions through a neuroscience-informed clinical approach.
Its objective is to connect structured clinical observation with clear, human-centered therapeutic strategies that may later support broader clinical development and professional collaboration.
A clinical vision for nervous system regulation
Synativ develops a clinical approach focused on nervous system regulation, structured observation, and therapeutic adaptation for chronic pain and functional recovery.
Clinical Focus Areas
- Chronic pain and central sensitization
- Migraine and sensory processing disorders
- Fibromyalgia and chronic widespread pain
- Neurofunctional rehabilitation and motor control
- Autonomic nervous system regulation
Clinical Approach
- Structured clinical observation
- Targeted sensory and proprioceptive stimulation
- Autonomic nervous system regulation
- Progressive therapeutic adaptation
- Individualized recovery pathways
Clinical & Scientific Dialogue
Synativ is open to dialogue with clinicians, researchers, and institutions interested in bridging clinical practice, rehabilitation, and neuroscience-informed care.
- Pain science and clinical reasoning
- Migraine-related therapeutic approaches
- Fibromyalgia and chronic pain pathways
- Motor control and rehabilitation perspectives
- Applied clinical implementation
Clinical Development Platform
The initiative is designed to support clinical structuring, pilot observations, and the progressive development of clear therapeutic models grounded in real-world practice.
- Structured clinical implementation
- Real-world therapeutic environments
- Scalable clinical frameworks
- Non-pharmacological care strategies
Educational resources and professional development
Synativ develops structured educational resources designed to support professional transmission, clinical reasoning, and neuroscience-informed therapeutic approaches.
Grounded in structured clinical observation and neuroscience-informed therapeutic frameworks developed through real-world practice.
Clinical Training Programs
Structured programs designed to transmit clinically-informed therapeutic methods at the intersection of neuroscience, manual therapy, and patient-centered care.
- Advanced clinical training
- Manual and sensory-based methods
- Professional development
- Structured therapeutic reasoning
Books & Publications
Clinical publications designed to structure therapeutic reasoning and make neuroscience-informed clinical perspectives accessible and transmissible.
- Clinical books and publications
- Neuroscience-informed reflections
- Editorial platform and open contributions
- Structured knowledge dissemination
Neuroscience-Informed Foundations
Scientific references that inform the Synativ framework (no direct institutional affiliation).
Synativ is informed by published contributions in chronic pain, fibromyalgia, migraine, affective touch neuroscience, and rehabilitation science.
Fibromyalgia, nociplastic pain, central sensitization, and central nervous system contributions to chronic pain.
Chronic musculoskeletal pain, pain modulation, rehabilitation science, and non-pharmacological approaches to pain.
Migraine neurobiology, sensory processing, and neurological mechanisms involved in headache disorders.
Affective touch, sensory physiology, and neural mechanisms involved in touch perception.
About Haim Berrebi
Clinical vision, field experience, and the development of the Synativ framework.
Professional & Clinical Collaboration
For professional inquiries, clinical collaboration, institutional dialogue, and pilot program discussions.
